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Are statins often ineffective?

Or are docs simply failing to use them correctly?

By Richard N. Fogoros, M.D., About.com

Updated: October 13, 2003

About.com Health's Disease and Condition content is reviewed by our Medical Review Board

Oct 13 2003
In a new study reported last week in Dublin, less than half the patients treated in the United Kingdom with statin drugs successfully reached targeted reductions in cholesterol levels.

Of 14,000 patients evaluated, only 48% had successful treatment. The study also noted that a large number of these patients did not have their cholesterol levels re-checked as recommended after beginning statins, and never had their starting doses increased. Interestingly, the doctors thought their performance was just fine. Over 80% of doctors reported their patients were achiving targeted cholesterol levels.

What this study means

This study does not mean that statin drugs don't work. They do.

What this study indicates is that, even when doctors are on the ball enough to aggressively treat cholesterol, they often don't follow through to make sure they are doing it right. Once again, patients need to make sure their doctors (who almost certainly mean well) are doing the appropriate follow-up.

When statins are begun, not only do cholesterol levels need to be monitored and drug doses adjusted appropriately, but also liver and muscle enzymes should be checked to rule out the most significant side effects of statins.

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