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Aspirin cuts death rate in people without known heart disease
January 22, 2001

In a recent study published in Lancet, patients who had no known cardiovascular disease, but who had at least one risk factor for cardiovascular disease, experienced a significant reduction in cardiovascular death by taking low-dose aspirin.

In this study, 4495 patients in Italy were randomized to either receive 100 mg of aspirin per day, or placebo. After 3.6 years, those who took aspirin had 44% fewer  deaths from cardiovascular problems.

Prior studies have documented a reduction in mortality in patients with known coronary artery disease who took aspirin (so-called secondary prevention.)  This new study lends credence to the notion that aspirin would also be beneficial to individuals who do not yet have heart disease, but who have risk factors for heart disease

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