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Richard N. Fogoros, M.D.

High-Glycemic-Index Diet Linked To Coronary Artery Disease In Women

By April 22, 2010

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A new study published in the Archives of Internal Medicine suggests that women who eat a high-gycemic diet have an increased risk of develping coronary artery disease. (A high-glycemic diet includes a lot of rapidly-absorbed carbohydrates. These are the kinds of carbohydrates most commonly found in processed foods, pastries and other baked goods, and candies. Here's more on high-glycemic foods.)

Investigators in Italy reported on over 47,000 volunteers who filled out a questionnaire on diet, then were followed for about eight years. Women who reported a high-carbohydrate diet (especially a high glycemc-index carbohydrate diet) were nearly twice as likely to develop coronary artery disease during the follow-up period than women who ate a low-carbohydrate diet. The same finding was not seen in the men in this study.

This study is consistent with a recent Cochrane review, which found that low-glycemic diets produced better weight loss and lipid profiles than other kinds of diets.

So, despite the continued emphasis by most cardiology professional societies on low-fat diets, the evidence continues to accumulate that low-carbohydrate diets - especially diets that emphasize low-glyemic-index carbohydrates - are beneficial for the heart. The "low fat vs. low carb" controversy continues, but it appears we are moving closer to a verdict.


Sieri S, Krogh V, Berrino F, et al. Dietary glycemic load and index and risk of coronary heart disease in a large Italian cohort. The EPICOR study. Arch Intern Med 2010; 170:640-647.

Thomas DE, Elliott EJ, Baur L. Low glycaemic index or low glycaemic load diets for overweight and obesity. Cochrane Database Syst Rev 2007; 3: CD005105.

April 23, 2010 at 11:40 am
(1) Diane Kress, RD CDE says:

The Metabolism Miracle by Diane Kress, RD CDE is the first lifestyle program written specifically for anyone with metabolic syndrome…a compilation of medical conditions including midline obesity, hypertension, hyperlipidemia/hypertriglyceridemia, prediabetes/type 2 diabetes. It is now a New York Times Best seller and is the #1 diet book in the UK after a 4 day syndication as the Daily Mail’s #1 diet book of 2010! It’s been licensed in Spanish and Indonesian.
Written by a traditonally trained, but open minded Registered Dietitian, Certified Diabetes Educator with over 25 years experience as a weight loss, cardiovascular, and diabetes specialist, it is based on all the latest science and written for the general public.
Bottom line: the diet we preached for years to lower weight, cholesterol, diabetes, blood pressure (the standard low calorie, low fat, low cholesterol diet) does NOT work for over 50% of the overweight population due to their tendency toward over-release of the fat gain hormone insulin!
Check it out at http://www.themetabolismmiracle.com. All the information is there.

April 23, 2010 at 11:46 am
(2) Diane Kress, RD CDE says:

I just realized that I can’t leave a website that is considered commercial. I consider the website I listed in the previous comment left by Diane Kress to be very educational….but if the comment would be removed because of it, I’m reposting without the site as I really want to get this information to those who need it most. It is in agreement with DrRich’s article post. thanks

April 26, 2010 at 11:03 am
(3) Hensylee says:

uh oh. I must print this one and pass it around to family members and friends. Too many of us are overeating high glycemic foods.
Thank you, Dr Rich.

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