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For companies trying to develop antiarrhythmic drugs, the "Holy Grail" has been to make a drug that is as effective as amiodarone, but without the toxicity of amiodarone. Recently, the highest hopes have been held for a cousin of amiodarone, an agent called dronedarone. The first results from long-term clinical trials with dronedarone now have been reported. Read why many are disappointed with the results here.
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